Weird title, but it says so in the title screen...
The Japanese part of the title actually means apocalyptic "how to spend the world's end". A World's end and Weekend are both pronounced "shuumatsu" so it's a pun with "how to spend the weekend" which sounds less serious.
2+ version plays only PSG while turbo R version plays FM sound.
Was originally a Windows game then was then ported to MSX.